| IMU Research Projects 2006 |
|---|
| No. | Project Leader/Investigators | Project Title | Grant No. |
| 1 | Ammu Radhakrishnan, Dashayani Mahalingam, Kalanithi Nesaratnam, Nurjahan Ibrahim | The effect of vitamin E supplementation on immune response to tetanus toxoid immunisation in normal human volunteers (January 2006-June 2007) | Grant: IMU 103-06 |
| 2 | Lee Lai Kah, Krishnan R | The use of car occupant restraints in Selangor, Malaysia (January-December 2006) | Grant: IMU 104-06 |
| 3 | Ong Kok Hai, Vishna Devi Nadarajah, Kandasami Palayan, Devaraj Balasingh, Manisekar Subramaniam, Rao GV, Thong Kwai Lin | Detection of carrier state in Salmonella typhi (January 2006-March 2008) | Grant: IMU 105-06 |
| 4 | Venkatesan Moorthy Rao, Ammu R, Pillappan Ramkumar, Rawat KS | Study of antioxidant and cytotoxic effects of Artemisia pallens (February 2006-March 2007) | Grant: IMU 106-06 |
| 5 | Teng Cheong Lieng, Mastura Ismail, Leon Piterman, Sangiva Wijesinha, Mimi Omar | Are diabetic patients attending government health clinics ready for self- monitoring of blood glucose? (January-December 2006) | Grant: IMU 107-06 |
| 6 | Nadeem Irfan Bukhari, Abu Bakar Majeed, Saringat H Bai, Yuen Kah Hay, Rosa Elizabeth, Kang Yew Beng | Preparation and characterisation of polymeric particulates as an oral delivery system for cefotaxime (March 2006-January 2007) | Grant: IMU 108-06 |
| 7 | Boo Nem Yum, Lim Siu Min, Lau Kok Fang, Koh Keng Tat, Tan Kah Kee, Ravindran Jegasothy | Inter-pregnancy interval as a predictor of low birth weight infants in Malaysian population (March-December 2006) | Grant: IMU 109-06 |
| 8 | Lai Nai Ming, Teng CL, Zainurashid Zainuddin, Ramesh Jutti, Chan Tze Haw, Liau Fei Chuen, Hapiza Baharom | The change in the knowledge and skills in evidence based medicine for undergraduate students following a structured teaching programme, as measured by an adapted Fresno Test (March 2006-June 2007) | Grant: IMU 110-06 |
| 9 | Thanikachalam P, Mak JW, Kasemsuk Yothasamutr | Study of parasitic infections in acute appendicitis in Batu Pahat (April 2006- February 2007) | Grant: IMU BMS I01-06-01 |
| 10 | Judson JP, Vishna DN, Gerald Lee Yew Min, Ravindran J, Noor Hidayah Ishak, Phang MF | Maternal serum soluble FMS-like tyrosine kinase (sFlt1) and placental growth factor (PIGF) concentrations as reliable biochemical markers of pregnancy induced hypertension (PIH) (April 2006- February 2007) | Grant: IMU BMS I01-06-02 |
| 11 | Ramkumar Pillapan, Ammu R, Venkatesan Rao M, Adrian Lim Fung Kin | Study of antioxidant and cytotoxic effects of Embelia ribes on cell lines (April 2006-February 2007) | Grant: IMU BMS I01-06-03 |
| 12 | Chu WL, Mak JW, Goh Ying We | Biological activity of extracts from marine algae (seaweeds) against the protozoan Acanthamoeba (April 2006-February 2007) | Grant: IMU BMS I01-06-04 |
| 13 | Ong CE, Rajinder Singh a/l Harhit Singh, Rusli Ismail | Study on the catalytic activity and protein stability of cytochrome P450 2C8(CYP2C8) allelic variants carrying mutation at amino acid lle264 (April 2006-Febraury 2007) | Grant: IMU BMS I01-06-05 |
| 14 | Vishna DN, Judson JP, Elena How Pei Ling, Ravindran J, Yusri, Noor Hidayah Ishak | Preliminary investigation on the serum levels of leptin and adiponectin in women with and without pregnancy induced hypertension (PIH) in relation to maternal BMI (April 2006-February 2007) | Grant: IMU BMS I01-06-06 |
| 15 | Chakravarti S, Kandasamy P, Azizan, Shareefah Emila, Linda | Role of apoptosis and abnormalities in expression of bcl-2 in benign nodular hyperplasia (April 2006-February 2007) | Grant: IMU BMS I01-06-07 |
| 16 | Yeoh Peng Nam, Soh Kai Sam, Tan Tze Jian | Effect of standardized Gingko biloba extract in isolated rat aorta (April 2006-February 2007) | Grant: IMU BMS I01-06-08 |
| 17 | Er Hui Meng, Ammu R, Cheng En-Hsiang | Anticancer activities of crude methanolic and water extracts of Pereskia bleo via apoptosis in mammary cancer cell lines (April 2006-February 2007) | Grant: BMS I01-06-09 |
| 18 | Nagaraja HS, Ammu R, Kumar P | Effect of bioactive flavonoid quercetin on stress induced changes in hypothalamo-pituitary-adrenal axis function, cytokine levels and lipid peroxidation (May 2006-April 2008) | Grant: IMU 111-06 |
| 19 | Ong Chin Eng, Tiong Kai Hung, Yap Beow Chin, Tan Eng Lai, Rusli Ismail | Cytochrome P450 (CYP2A6): in vitro studies on genetic polymorphism and drug-flavonoid interaction (June 2006-November 2008) | Grant: IMU 112-06 |
| 20 | John Paul Judson, Vishna DN, Kamalan Jeevaratnam, Sivalingam Nalliah, Mohammad Farouk Abdullah, Ravindran J, Magendra | Structural and vascular changes in the placenta and umbilical cord and its association with maternal levels of selected biomarkers in preeclampsia (June 2006-May 2008) | Grant: IMU 113-06 |
| 21 | Hee Chee Seng, Ammu R, Gun Suk Chyn, Asmah Mohd, Ghandhi C | Comparison of the relationship between the expression of IL-12-beta-2- receptor (IL-12_2R) and CD30 on surface of T-lymphocytes and disease manifestation in systemic lupus erythrematosus (SLE) and rheumatoid arthritis (RA) patients from Hospital Seremban (July 2006-June 2007) | Toray Foundation Malaysia RO18-06 |
| 22 | Ammu R, Dashayini Mahalingam, Kalanithin Nesaretnam | The effect of vitamin E supplementation on the immune response to tetanus toxoid immunisation in a mouse model (July 2006-June 2007) | Grant: IMU 114-06 |
| 23 | Kumar P, Srikumar Chakravarty, Nilesh Kumar | Study of neuroprotective and neuromodulatory effects of Centella asiatica on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced changes in Pakin gene expression (July 2006-July 2007) | Grant: IMU 115-06 |
| 24 | Ooi Aik Seng, Kang Yew Beng, Simon Mackay | Development of an enzyme conjugated HIV-1 envelope protein, gp120 for application in a spectrophotometric gp 120-ligand binding kinetic assay (July 2006-June 2008) | Grant: IMU 116-06 |
| 25 | Vishna DN, Shah Mariam Mohamad, Lee Han Lim, Barathy Rani Ramasamy | Isolation and characterisation of vegetative proteins expressed in mosquitocidal Bacillus thuringiensis (7 strains) and Bacillus sphaericus (2 strains) isolated from Malaysian soil (August 2006-July 2007) | Grant: University of Melbourne R20-2006 |
| 26 | Chiu Chee Kidd, Siong Heng Kock, Tey Yee Sin, Ung Wan Sin, Siow Yee Lein, Tey Tu Lip, Pravin, Sim, Pazli | Clinical effectiveness, vitamin B12 analogue, in treating low back pain (September-December 2006) | Grant: IMU 117-06 |
| 27 | Khin Ye Myint, Nurjahan Mohd Ibrahim, Ramli Ahmad, Sagili Chandrasekhara Reddy, Phua Kai Lit | Ethnic differences in the responsiveness to ACEI/ARB in type 2 diabetes mellitus with microalbuminuria (September 2006-October 2007) | Grant: IMU 118-06 |
| 28 | Kenny Voon Gah Leong, Chua Kaw Beng, Yasmin Ab Malik, Linfa Wang | Molecular characterization of two novel orthoreoviruses isolated in Malaysia (August 2006-July 2008) | Grant: IMU 119-06 |
| 29 | Tan Eng Lai, Gan Sook Yee, Sam Choon Kook | Epstein-Barr virus latent membrane protein 1: its roles in invasion and metastasis in nasopharyngeal carcinoma (January 2007-December 2009) | Grant: Makna Cancer Foundation RO19-06 |
| 30 | Nilesh Kumar Mitra, Vishna Devi Nadarajah, How Hee Siong | Examination of exposure of chlorpyrifos and concurrent exposure of stress and chlorpyrifos on neurons of forebrain regions in adult mice (November 2006-October 2007) | Grant: IMU BMS I02-06-01 |
| 31 | Ammu R, Vijaya Lechimi Raj, Tan Lee Keng, Liam CK, Rakesh Naidu | Association of interleukin-13 (IL-13) gene polymorphisms with plasma IgE levels and IL-13 production in Malaysian asthmatics: a pilot study (November 2006-October 2007) | Grant: IMU BMS I02-06-02 |
| 32 | Shar Mariam Mohamed, Chu WL, Michelle Ho Shean Kyun | Carregenan as a protective agent against ultraviolet radiation-induced toxicity and mutagenicity (November 2006-October 2007) | Grant: IMU BMS I02-06-04 |
| 33 | Chen Yu Shui, Judson JP, Lee Kah Heng | The effect of water extracts of Euphorbia hirta on the expression of matrix metalloproteinases and tissue inhibitor of matrix metalloproteinases in rat articular cartilage (November 2006-October 2007) | Grant: IMU BMS I02-06-05 |
| 34 | Vishna DN, Judson JP, Sivalingam N, Tee Kok Chuan, Ravindran J, Farouk A | Detection of autoantibodies against angiotensin receptors (AT1) in women with pregnancy induced hypertension (PIH) (November 2006-October 2007) | Grant: IMU BMS I02-06-06 |
| 35 | Thanikachalam MP, Ang Seng Long, Kandasamy P, Azizan, Shareefah Emilia, Chakravati S | A study of diagnostic utility of special stains in oesophageal and gastric biopsies (November 2006-October 2007) | Grant: IMU BMS I02-06-07 |
| 36 | Nagaraja HS, Srikumar C, Mun Yee | Effect of bioflavone 4', 5', 7-trihydroxy-flavone (Aginenin) on cyclosporine induced nephrotoxicity (November 2006-October 2007) | Grant: IMU BMS I02-06-08 |
| 37 | Francis I Achike, Terry Wong Chin Pin, Mohd Rais Mustafa | Influence of acidosis on diabetic vascular tissue responses to acute treatment with the antioxidant flavonoid, quercetin (November 2006-October 2007) | Grant: IMU BMS I02-06-09 |
| 38 | Pillappan Ramkumar, Chuang Jin-Yu, Shar Mariam M | Study of antioxidant and cytotoxic effects of the standardised Kaempferia galangal extract and its fractions in vitro in epithelia cells from breast cancer cell lines (November 2006-October 2007) | Grant: BMS I02-06-10 |
| 39 | Lai Nai Ming, Teng CL, Sivalingam N, Ramesh J, Liau Fei Chuan, Hapizah Baharom | Measuring competence in evidence based medicine: the correlation between the adapted Fresno Test and Berlin Questionnaire (January 2007- December 2007) | Grant: IMU 120-06 |
| 40 | Ammu R, Shalini Sree Kumar, Cheong Soon Keng, Noor Hamidah Hussin | To investigate the therapeutic effect of recombinant mouse cytokines (e.g. IL-18, IL-15) in murine breast cancer model (October 2006-September 2008) | Grant: IMU 121-06 |
| 41 | Yeoh Peng Nam, Mak JW, Ong CE, Valsala Ramachandran | Effect of Morinda citrifolia extract on human blood coagulation in vitro (October 2006-September 2008) | Grant: IMU 122-06 |
| 42 | Shar Mariam Mohamed, Rebecca Wong Shin Yee, Vishna DN | A study on the mechanism of cell death induced by Bacillus thuringiensis 18 toxin on leukemic cells (January 2007-December 2008) | Grant: IMU 123-06 |
| 43 | Yeoh PN, Ong CE, Peter Pook, Hirotaka Onishi, Lim Meng Hui, John Ling Kie Yieu | Perceptions of pharmacy students on problem-based learning as a learning tool in the pharmacy curriculum (November 2006-October 2008) | Grant: IMU 124-06 |
| 44 | Sivalingam N, Ammu R, Shabnanm Montazeri, Zainur Rashid, Krishna Kumar, Ravidran Jegasothy | The predictive value of single nucleotide polymorphism (SNP) of the human tumour necrosis factor-alpha (TNF_) and interleukin-10 (IL-10) in human gestational diabetes (December 2006-November 2008) | Grant: IMU 125-06 |
| 45 | Esha Das Gupta, Zainab Abd Majeed, Nayyer Naveed Wazir, Teng CL, Loh KY, Yeap Swan Sim | Depression and chronic pain in osteoarthritis (November 2006-October 2007) | Grant: IMU 126-06 |
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